Identification of new genovariants of canine distemper virus in dogs from the State of el análisis del gen de la nucleocápside en perros del Estado de México.

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The sequences of these genovariants, along with the sequences of other isolates reported worldwide were analyzed in a phylogenetic tree.

Another contribution of this work is related to the identification of new sequences of the N gene. With time, this tic usually diminishes somewhat in its severity. Therefore, the pathogenic genovariants posses seven conserved changes, which allow differentiate them from the vaccine strain Onderstepoort table 2. Identification of new genovariants of canine distemper virus in dogs from the State of Mexico by analyzing the nucleocapsid gene.

Kind Hearts in Action. Archived from the original on 18 January This article is about a disease generally affecting animals in the order Carnivora. Retrieved 30 September Todos los perros deben ser vacunados contra el distemper.

Canine distemper

The results show the formation of two main groups, one that includes only the isolates of the State of Mexico, and another formed by two sub-groups. Trends Microbiol 3, Journal of Molecular Evolution. Distemper, or hardpad disease in canines, [14] affects animals in the families Canidae dog, fox, wolf, Raccoon dogMustelidae ferret, mink, skunk, wolverine, marten, badger, otter[11] [14] Procyonidae raccoon, coatiAiluridae red pandaUrsidae bearElephantidae Asian elephantand some primates e.


A thickening of the footpads sometimes develops, and vesicular pustular lesions on the abdomen usually develop. Jorge Guerrero November 6, The viral infection can be accompanied by secondary bacterial infections and can present eventual serious neurological symptoms.

Canine distemper – Wikipedia

The phylogenetic distance scale bar indicates the estimated changes per nucleotide. Arq Bras Med Vet Zootec 59, Advances in veterinary medicine.

Puppies, especially, have damage to the enamel of teeth that are not completely formed or those that have not yet grown through the gums. Characterization of monoclonal antibodies directed against the canine distemper virus nucleocapsid protein. This first round of fever typically recedes rapidly within 96 hours, and then a second round of fever begins around the 11th or 12th day and lasts at least a week. Archived from the original on June 25, CDV has an envelope composed of a membrane protein termed M and two glycoproteins, the hemagglutinin termed H and the fusion protein termed F Mochizuki et al ; the genomic RNA is tightly bound to the nucleocapsid protein, termed N; the major structural protein.

The animal may also show signs of sensitivity to light, incoordination, circling, increased sensitivity to sensory stimuli such as pain or touch, and deterioration of motor capabilities.

Retrieved October 31, Epidemiological studies of the disease in this country have not been made, probably due to the lack of information about the molecular characteristics of the CDV isolates in the different geographical areas of this country.


Dog diseases Animal virology. These affected teeth tend to erode quickly. These strays act as a reservoir for the virus, spreading it throughout the surrounding area, including urban areas. Recent Advances in Canine Infectious Diseases.

By using this site, you agree to the Terms of Use and Privacy Policy. Archived PDF from the original on Puppies and dogs that have not received their shots can then be perrow in a place where many dogs interact, such as a dog park. The virus initially replicates in the lymphatic tissue of the respiratory tract. No specific treatment for the canine distemper is known. However, several febrile diseases match many of the signs of the disease and only recently has distinguishing between canine hepatitisherpes virus, perosand leptospirosis been possible.

Stettler M, A Zurbriggen. Canine distemper sometimes termed hardpad disease is a viral disease that affects a wide variety of animal families, including domestic and wild species of dogs, coyotes, foxes, distempfr, wolves, ferrets, skunks, raccoons, and large cats, as well as pinnipeds, some primates, and a variety of other species.

The virus first appears in bronchial lymph nodes and tonsils 2 days after exposure. Thank you for subscribing.