Both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. Key words: Leucas aspera, Antibacterial activity. Leucas aspera, Leucas zeylanica, antifungal, dermatophytes. RESULTS: Antifungal activity of Leucas sp. against Dermatophytes. Objective: The aim of this study was to explicate antibacterial, antifungal, and antioxidant activities of Leucas aspera flowers. Methods: Antibacterial activity was.

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Click here to sign up. An overview of nosocomial infections, including the role of the microbiology laboratory. It has been reported that there is an inverse relationship between antioxidative status and incidence of human diseases such as cancer, aging, neurodegenerative disease, and atherosclerosis [3]. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically.

Leucas aspera, Leucas zeylanicaantifungal, dermatophytes. This asprea could lead to new drug discovery or advance the use of indigenous herbal medicines.

Seed oil against multi-drug resistant bacteria from clinical isolates. Drug discovery from medicinal plants. Int J Food Microbiol ; Preliminary antinociceptive, antioxidant and cytotoxic activities of Leucas aspera root. The antibacterial activity of Leucas aspera was studied using double diffusion method and the activity was tested against the human pathogens like Bacillus cereus,Klebisella pneumoniae,Staphylococcus aureus,Pseudomonas aeruginosa and Enterobacter faecalis.

The increase in resistance of microorganisms encouraged scientists to search for new antimicrobial agents from plants. F and Riley T.

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The toxicity effect of L. This was the first report that Leucas zeylanica showed antifungal activity against these dermatophytes. The medicinal properties of plants have been investigated due to their potent pharmacological activities, low toxicity and economic viability [1].

The IC 50 value 6. It may be attributed to the fact that the plant extracts being in crude form contain leufas smaller concentrations of bioactive compounds [18]. Antimicrobial and phytochemical studies on 45Indian medicinal plants against multidrug resistant human pathogens.


Ethanobotanical Leaflets, 13, Biotechnology of medicinal plants-recent advances and potencial. LabiateaeVitis vinifera L. It should be emphasized that toxic effect of the antioxidant and antimicrobial agent on the host cells must be considered, as a substance may exhibit antioxidant and antimicrobial activity by virtue of its toxic effect on the cells [22].

Brine shrimp lethality bioassay of root extract Brine shrimp lethality bioassay was carried out according to Meyer et al [16] to investigate the cytotoxicity of the root extract. All the plant parts root, flower, leaf and stem were ground into powdered form with a grinder. anhimicrobial

Materials and methods 2. The scavenging activity of these extracts was lower compared with both antioxidants, BHT Screening of Amazonian plants from the adolphoducke forest reserve, Manaus, state of Amazonas, Brazil, for antimicrobial activity. Collection of plant material: In this work two species of the genus Leucas have been chosen Leucas aspera and Leucas zeylanica.

The results of this study support the use of Leucas aspera and Leucas zeylanica in traditional Indian medicine and show that methanolic leaf extract of these plants can be used as an easily accessible source of natural antifungal agent and can be of assistance in some dermatological problems. At a higher concentration, these extracts may exhibit more significant free radical scavenging activity.

Search for novel antifungal agents with wide range of structural classes acting on selectively new targets with fewer side effects has been going on. Journal of American Medical Association, 49, The percentage of scavenging of all the plant extracts root, flower, leaf and stem was compared with positive controls.

They are very efficient in treating contagious diseases without extenuating any harmful side effects that are related to pharmaceutically available antimicrobials 2.

Antimicrobial activity of Leucas aspera flowers. The major chemical substances of interest in these surveys were the alkaloids and steroidal sapogenins, however other diverse groups of naturally occurring phytocomponents such as flavanoids, tannins, unsaturated sterols.


In this study, the antibacterial activity of the different parts of L. It is used as an insecticide and indicated in traditional medicines for coughs, cold, painful swelling and chronic skin eruption. The presence of alkaloids, steroids, tannins, flavonoids and glycosides were confirmed during preliminary phytochemical screening of this plant Natural products as sources of new drugs over the period Antimicrobial activity of certain Indian medicinal plants used in folkloric medicine.

O and Navarro D. Determination of in vitro antioxidant activity of fennel Foeniculum vulgare seed extract.

Many reports of antibacterial activity of plants extracts against human pathogens and their pharmaceutical application are available. Antiinflammatory activity of different fractions of Leucas aspera Spreng.

Antioxidant and antibacterial activity of different parts of Leucas aspera

Similarly the study performed by 13 showed the antifungal activity of ethanol and methanol extract of Spilanthes paniculata against Aspergillusniger, at the same time it is also stated in the above study that ethyl acetate extract of Leucas aspera also showed the antifungal effect against Aspergillusniger, where as in this experiment methanol extract of leaf of Leucas aspera and Leucas zeylanica exhibited antfungal activity against Aspergillus flavus which is reported for the first time.

Activiity of Food Safety, 6, Further studies might aim at the isolation and identification of active substances from the active plant extracts which could also disclose compounds with better therapeutic value.

In this study, we would like to compare the antioxidant activity of methanol extract from different parts of L. In a research conducted by using the entire plant of L.